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Everything you do, everything you say, every choice you make, sooner or later comes back around.

INFORMATION FROM THE CANCER CONTROL SOCIETY CONVENTION OF 2017

Happy Sunday,

FOOD FOR THOUGHT TODAY; if you want change then make changes, if you want to be treated well then treat others well, if you want to be loved than love others. Don’t expect to get something when you aren’t doing it yourself. Too many people expect perfection from others yet fail to give out what they expect.

“Sow a thought, and you reap an act; Sow and act, and you reap a habit; Sow a habit and you reap a character; Sow a character, and you reap a destiny.” Charles Reade

You are never given a wish without also being given the power to make it true. You may have to work for it, however.

The world is your exercise-book, the pages on which you do your sums. It is not reality, although you can express reality there if you wish. You are also free to write nonsense, or lies, or to tear the pages. The original sin to limit the is. Don’t! – From the book ILLUSIONS

Continuing on INFORMATION FROM THE CANCER CONTROL SOCIETY CONVENTION OF 2017, vitamins and minerals. Today I’m going to blog on another supplement that I do for my home program to manage my cancer, melatonin.

Melatonin is a hormone in your body that plays a role in sleep. The production and release of melatonin in the brain is connected to time of day, increasing when it's dark and decreasing when it's light. Melatonin production declines with age.

Melatonin is also available as a supplement, typically as an oral tablet. Most melatonin supplements are made in a lab.

People commonly use melatonin for sleep disorders, such as insomnia and jet lag.

Unlike with many sleep medications, you are unlikely to become dependent on melatonin, have a diminished response after repeated use (habituation) or experience a hangover effect.

Melatonin is a natural inducer of hypothermia, inhibiting the growth rate of established tumors through the retardation of tumor metabolism and development by lowering the body temperature.

In addition, melatonin both induces antioxidants as well as demonstrates preventive antioxidant capability, which in turn blocks free radical damage to normal cells while limiting oxidative damage to DNA, lipids, amino acids and proteins.

Administration of supplemental melatonin has been shown to be beneficial even in the supportive care of advanced and end stage cancer. The body’s ability to produce melatonin is reduced in most cancer patients. However; even in the unfortunate circumstance in which cancer has already overwhelmed the bodies innate cancer fighting capabilities supplemental melatonin can play a critical role in the defense system against cancer’s progression.

Melatonin has been shown to lessen tissue wasting as well as diminish weight loss, fatigue, weakness and depression. It can enhance immune function, improve wound healing, and improve overall quality of life and survival rates.

Melatonin impacts common symptoms found in patients with advanced cancer and/or are undergoing chemotherapy, by counteracting anemia and lymphocytopenia, stimulating platelet production, enhancing appetite and diminishing pain including bone pain through its natural analgesic properties.

Melatonin can activate the cytokine system which exerts growth-inhibiting properties and by stimulating the cytotoxic of macrophages; monocytes which are responsible for immunological and inflammatory defense processes against bacterial, viral, fungal and neoplastic pathogens.

There are substantial benefits considering that approximately half of all patients diagnosed with cancer die because of poor symptom management.

Melatonin levels in cancer patients are correlated with tumor aggressiveness and progression. For example; a high percentage of women with estrogen receptor positive breast cancer have low plasma melatonin levels. Melatonin inhibits human breast cancer cell growth, reduces tumor spread and invasiveness invitro.

Precisely how melatonin interferes with estrogen signaling is unknown, though research suggests that melatonin suppresses the epidermal growth factor receptor 3. In tumorigenesis studies melatonin reduced the incidence and growth rate of breast tumors and slowed breast cancer development. Prolonged oral melatonin administration significantly has been shown to reduce the development of exciting mammary tumors. In a metastatic hormone-refractory prostate cancer patient, oral melatonin 5mg/day induced disease stabilization for six weeks.

Extrapolating the melatonin levels observed in aging humans to the cellular level, one expects to find melatonin decreasing more rapidly in tumor cells than is the case with normal healthy cells; levels normalized through melatonin supplementation would have a negative growth advantage in the tumor micro-environment and would therefore inhibit tumor growth. Melatonin levels are depressed in individuals with cancer of different origins during the phase of primary tumor growth, whereas normal melatonin levels may be found when remission occurs.

It has been suggested that melatonin acts as a naturally occurring anti-estrogen on tumor cells, as it down-regulates hormones responsible for the growth of hormone-dependent mammary tumors.

Melatonin differs from the understood anti-estrogens such as tamoxifen in that it does not seem to bind to the estrogen receptor or interfere with the binding of estradiol to its receptor. At the same time, melatonin can increase the therapeutic efficacy of tamoxifen and biological therapies.

Numerous clinical studies by Lissoni et al show, melatonin adjuvant therapy favorably influences the course of advanced cancer, leading to an improved quality of life and increased survival. Compared with patients receiving supportive care only, cancer patients with untreatable advanced solid tumors receiving melatonin supplementation therapy experience significantly lower rates of catabolic wasting (cachexia), weakness (asthenia), platelet (thrombocytopenia) and white blood cell counts declines (lymphocytopenia).

JUST THE FIRST STEP ‼️🚦‼️

Wow, it's Sunday again‼️ Take the first step in faith ❤️ you don't have to see the whole staircase🚦 just the first step. Enjoy #inspiration, #motivation, #newbeginnings

Melatonin deficiencies in patients in more advanced stages of cancer may be due to altered circadian rhythm (disturbed sleep patterns), cancer related anorexia-cachexia and reduced food intake -melatonin is produced by the enterochromaffin cells in the gastrointestinal tract after food consumption. In turn, melatonin supplementation increases appetite, diminishes tissue wasting and restores sleep continuity in cancer patients. Administration of melatonin to patients with advanced cancer who have only short expected survival times results in some cases in disease stabilization and increase survival percentages at one to five years.